Minneapolis – October 15, 2026 -- Men in the U.S. can now get Roxus, a prescription nasal spray for erectile dysfunction (ED), through the telemedicine platform Mavrox, which ships it to their door.
Roxus comes from Australian pharmaceutical company LTR Pharma (ASX: LTP). It delivers vardenafil, the same type of ED medicine as Viagra, which has been used in tablets for more than 20 years. Instead of a pill, it uses LTR's proprietary intranasal spray technology.
Peak blood levels arrive in about 10 minutes in company studies
Roxus uses the same intranasal vardenafil formulation as SPONTAN, LTR's nasal spray that has been prescribed in Australia for the past two years. In clinical studies, including a peer-reviewed Phase 1 study, the spray reached peak blood levels in a median of about 10 minutes. Vardenafil tablets take 45 to 60 minutes.
Men 65 and older reached peak levels just as quickly, and the spray did it with a quarter of the tablet dose. Because the drug is absorbed through the nose rather than the stomach, it is designed to avoid the delays a heavy meal can cause with pills.
LTR Pharma Executive Chairman Lee Rodne said the spray is "effective within 5-10 minutes." Urologist Dr. Amy Pearlman, a member of LTR's Scientific Advisory Board, pointed to speed, discretion and spontaneity as the focus of the new delivery method.
The comparison data come from pharmacokinetic studies of SPONTAN and published prescribing information for oral PDE5 inhibitors. No head-to-head study has compared Roxus with other ED treatments.
Men can get a prescription online through Mavrox
LTR Pharma has partnered with Shed, which operates the men's health telemedicine platform Mavrox. Men complete a short online health assessment at Mavrox.com/Roxus, and a licensed U.S. provider reviews it. If Roxus is appropriate, Strive Pharmacy fills the prescription and ships it discreetly. Men who prefer an in-person visit can ask their healthcare provider about Roxus.
Nitrates, poppers and riociguat rule out use
Men should not use Roxus if they take nitrates for chest pain, recreational "poppers," or riociguat, or if they are allergic to vardenafil. Providers should know about any heart, liver or kidney problems and all medicines a patient takes. An erection lasting more than 4 hours, or sudden vision or hearing loss, requires emergency care. Common side effects include headache, flushing, runny or stuffy nose, indigestion and temporary nasal discomfort.
Roxus is a compounded medication, prepared for an individual patient on a valid prescription. The U.S. Food and Drug Administration (FDA) has not reviewed or approved it for safety or efficacy. Compounded drugs are intended for patients whose prescriber has determined that an available FDA-approved drug does not meet their needs.